Changes to the structure and dynamics in mutations of Aβ(21-30) caused by ions in solution.

@article{Smith2013ChangesTT,
  title={Changes to the structure and dynamics in mutations of Aβ(21-30) caused by ions in solution.},
  author={Micholas Dean Smith and Luis A. Perera Cruz},
  journal={The journal of physical chemistry. B},
  year={2013},
  volume={117 48},
  pages={14907-15}
}
The structure and dynamics of the 21-30 fragment of the amyloid β-protein (Aβ(21-30)) and its Dutch [Glu22Gln], Arctic [Glu22Gly], and Iowa [Asp23Asn] isoforms are of considerable importance, as their folding may play an important role in the pathogenesis of sporadic and familial forms of Alzheimer's disease and cerebral amyloid angiopathy. A full… CONTINUE READING