Changes to memory structures in children treated for posterior fossa tumors.

@article{Riggs2014ChangesTM,
  title={Changes to memory structures in children treated for posterior fossa tumors.},
  author={Lily Riggs and Eric Bouffet and Suzanne Laughlin and Normand Laperriere and Fang Liu and Jovanka Skocic and Nadia Scantlebury and Frank Y. Wang and Nicholas J Schoenhoff and Douglas R. Strother and Juliette Hukin and Christopher Fryer and Dina McConnell and Donald J Mabbott},
  journal={Journal of the International Neuropsychological Society : JINS},
  year={2014},
  volume={20 2},
  pages={
          168-80
        }
}
Children treated for medulloblastoma (MB) exhibit long-term impairments in declarative memory, but the pathophysiology underlying this is unclear. Previous studies report declines in global white matter volume, but have failed to link this to declines in memory performance. We examined the effects of treatment on measures of global brain structure (i.e., total white and gray matter volume) and specific memory structures (i.e., hippocampus and uncinate fasciculus). We used volumetric MRI and… CONTINUE READING

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