Changes to desmosomal antigens and lectin-binding sites during differentiation in normal human epidermis: a quantitative ultrastructural study.

@article{Skerrow1989ChangesTD,
  title={Changes to desmosomal antigens and lectin-binding sites during differentiation in normal human epidermis: a quantitative ultrastructural study.},
  author={Christine J. Skerrow and D G Clelland and D Skerrow},
  journal={Journal of cell science},
  year={1989},
  volume={92 ( Pt 4)},
  pages={667-77}
}
During epidermal differentiation, desmosomes undergo a series of changes in their abundance, structure and properties, which has previously been defined by conventional electron microscopy and the use of antibodies to desmosomal proteins at the light-microscope level. Such changes in a major adhesive organelle would be expected to have a significant role in the maintenance of epidermal organization, and therefore require more detailed characterization. In the present study, modifications to… CONTINUE READING