Changes of urinary and blood porphyrin profiles by exposure to PCBs, lead or diazinon in rats.

Porphyrin profiles in excreta or blood have been useful biomarkers for monitoring exposure of hazardous xenobiotics to human or animals. We evaluated and compared the changes in urinary and blood copro-, uro-, and protoporphyrins during and after the exposure of Aroclor1254 (PCBs), lead (Pb) or diazinon to rats. PCBs (10, 50 and 100 mg/kg bw), Pb (62.5, 250… (More)