Changes of the adenine ribonucleotide content during preimplantation development of mouse embryos in vivo and in vitro.

@article{Spielmann1984ChangesOT,
  title={Changes of the adenine ribonucleotide content during preimplantation development of mouse embryos in vivo and in vitro.},
  author={H. Spielmann and Ursula Jacob-M{\"u}ller and Peter Schulz and Angelika Schimmel},
  journal={Journal of reproduction and fertility},
  year={1984},
  volume={71 2},
  pages={467-73}
}
The amount of ATP, ADP and AMP and also the adenylate energy charge and the ATP/ADP ratio were determined in preimplantation mouse embryos (strain NMRI) in vivo. The ATP content decreased from 0.64 pmol at fertilization to 0.21 pmol in late blastocysts. ADP decreased from 0.1 pmol in the zygote to 0.06 pmol in 4-8-cell embryos and increased again to 0.15… CONTINUE READING