Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy.

@article{Murmu2006ChangesOS,
  title={Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy.},
  author={Meena Sriti Murmu and Shiri Salomon and Yaarit Biala and Marta Weinstock and Katharina Braun and Joerg Bock},
  journal={The European journal of neuroscience},
  year={2006},
  volume={24 5},
  pages={
          1477-87
        }
}
Both chronic stress in adulthood and episodes of stress in the early postnatal period have been shown to interfere with neuronal development in limbic prefrontal cortical regions. The present study in rats showed for the first time that the development of layer II/III pyramidal neurons in the dorsal anterior cingulate (ACd) and orbitofrontal cortex (OFC) is significantly affected in offspring of mothers exposed to stress during pregnancy. In prenatally stressed (PS) male rat pups the ACd and… CONTINUE READING
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