Changes of serum levels of MMP-3, sRANKL, and OPG in juvenile-onset ankylosing spondylitis patients carrying different HLA-B27 subtypes

Abstract

Ankylosing spondylitis (AS) patients whose symptom onset occurs before 16 years of age are termed juvenile-onset ankylosing spondylitis (JAS). Investigations suggested that JAS had worse functional outcome, and abnormality of bone metabolism can appear in early stage of AS. The objectives of this study are to compare changes of serum inflammatory and bone… (More)
DOI: 10.1007/s10067-015-2940-z

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@article{Mou2015ChangesOS, title={Changes of serum levels of MMP-3, sRANKL, and OPG in juvenile-onset ankylosing spondylitis patients carrying different HLA-B27 subtypes}, author={Yi-Kun Mou and P. Zhang and Qiu-xia Li and Zhi-Ming Lin and Ze-tao Liao and Qiu-jing Wei and Jie-ruo Gu}, journal={Clinical Rheumatology}, year={2015}, volume={34}, pages={1085-1089} }