Changes of nucleic acid and protein synthesis in hypertrophied guinea-pig heart during intermittent hypoxia.

Abstract

The effect of intermittent normobaric hypoxia on nucleic acid and protein synthesis of guinea-pig heart was studied. De novo synthesis of purine nucleotides, of RNA and DNA, as well as RNA polymerase activities and protein synthesis, increased in the heart right ventricles of hypoxic animals compared to the controls. These results suggest an activation of… (More)

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@article{Alberghina1981ChangesON, title={Changes of nucleic acid and protein synthesis in hypertrophied guinea-pig heart during intermittent hypoxia.}, author={Mario Alberghina and Nicol{\`o} Ragusa and Anna Maria Giuffrida}, journal={The Italian journal of biochemistry}, year={1981}, volume={30 3}, pages={229-41} }