Changes of mitochondrial cytochrome c oxidase and FoF1 ATP synthase subunits in rat cerebral cortex during aging

@article{Nicoletti1995ChangesOM,
  title={Changes of mitochondrial cytochrome c oxidase and FoF1 ATP synthase subunits in rat cerebral cortex during aging},
  author={Vincenzo Giuseppe Nicoletti and Elisabetta A. Tendi and Calogera Lalicata and Samantha Reale and Antonella Costa and Roberto Federico Villa and Nicol{\`o} Ragusa and Prof. A. M. Giuffrida Stella},
  journal={Neurochemical Research},
  year={1995},
  volume={20},
  pages={1465-1470}
}
The contents of subunits I, II/III, and IV of cytochrome c oxidase and of subunits α, β and γ of FoF1 ATP synthase in inner mitochondrial membrane proteins purified from cerebral cortex of rat at 2, 6, 12, 18, 24, and 26 months of age were analyzed by western blot. Age-related changes in the content of subunits, either of mitochondrial or nuclear origin, were observed. All the cytochrome c oxidase (COX) subunits examined showed an age-related increase from 2-month-old rats up to 24 months with… CONTINUE READING
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