Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level.

@article{Wang2012ChangesOL,
  title={Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level.},
  author={Hui Wang and Zhipeng Xu and Chunsheng Feng and Y. M. Wang and Xingyuan Jia and Anshi Wu and Yun Yue},
  journal={Annales francaises d'anesthesie et de reanimation},
  year={2012},
  volume={31 3},
  pages={
          e61-6
        }
}
BACKGROUND AND PURPOSE It has not been clearly described for mechanisms of postoperative cognitive dysfunction (POCD), but not yet for narcotic in connection with POCD. Acetylcholine plays important roles in learning and memory especially in elderly people. It is not very clear that cholinergic changes in the hippocampus are in relation to spatial memory impairment. The effects of isoflurane, a commonly used inhalation anaesthetic, as well as acetylcholine on learning and memory in the brain… CONTINUE READING

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