Changes of labile metabolites during anoxia in moderately hypo- and hyperthermic rats: correlation to membrane fluxes of K+.

@article{Katsura1992ChangesOL,
  title={Changes of labile metabolites during anoxia in moderately hypo- and hyperthermic rats: correlation to membrane fluxes of K+.},
  author={Kenichiro Katsura and H Minamisawa and Anders Ekholm and Jaroslava Folbergrov{\'a} and Bo K. Siesj{\"o}},
  journal={Brain research},
  year={1992},
  volume={590 1-2},
  pages={6-12}
}
The objective of this study was to assess the influence of temperature on the coupling among energy failure, depolarization, and ionic fluxes during anoxia. To that end, we induced anoxia by cardiac arrest in anesthetized rats maintained at a body temperature of either 34 degrees C or 40 degrees C, measured extracellular K+ concentration (K+e), and froze the neocortex through the exposed dura for measurements of phosphocreatine (PCr), creatine (Cr), ATP, ADP, and AMP, glucose, glycogen… CONTINUE READING

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