Changes of hepatic sinusoids in experimental septicemia of rats are correlated with the production of nitrogen monoxide. A morphometrical and immunohistochemical study.


BACKGROUND/AIMS Two types of experimental septic models were prepared to morphologically and histometrically analyze the changes in the hepatic sinusoid. Furthermore, the local expression of nitrogen monoxide synthetase was analyzed by immunohistochemical and immune electron microscopical studies for the purpose of investigating the involvement of nitrogen… (More)