Changes of fractional anisotropy and apparent diffusion coefficient in patients with idiopathic normal pressure hydrocephalus.

@article{Demura2012ChangesOF,
  title={Changes of fractional anisotropy and apparent diffusion coefficient in patients with idiopathic normal pressure hydrocephalus.},
  author={Koichiro Demura and Mitsuhito Mase and Tosiaki Miyati and Tomoshi Osawa and Manabu Hattori and Harumasa Kasai and Masaki Hara and Yuta Shibamoto and Kiyofumi Yamada},
  journal={Acta neurochirurgica. Supplement},
  year={2012},
  volume={113},
  pages={29-32}
}
Since ventricular dilation and periventricular abnormal intensities are commonly seen in patients with idiopathic normal pressure hydrocephalus (INPH) on magnetic resonance imaging (MRI), dysfunction of white matter may have an important role in the mechanism causing symptoms of INPH. To clarify the pathophysiology of INPH, we analyzed axonal water dynamics using diffusion tensor MRI. Thirty-six patients with possible INPH were included. Regional fractional anisotropy (FA) and apparent… CONTINUE READING