Changes of diurnal rhythm and levels of total and free testosterone secretion from pre to late puberty in boys: testis size of 3 ml is a transition stage to puberty.

@article{AnkarbergLindgren2004ChangesOD,
  title={Changes of diurnal rhythm and levels of total and free testosterone secretion from pre to late puberty in boys: testis size of 3 ml is a transition stage to puberty.},
  author={Carina Ankarberg-Lindgren and Ensio Norjavaara},
  journal={European journal of endocrinology},
  year={2004},
  volume={151 6},
  pages={747-57}
}
OBJECTIVE To establish levels for comparison for 24-h total and free serum testosterone in prepubertal boys and throughout pubertal development. DESIGN The study subjects were 55 healthy boys, aged 5.0-18.6 years, who underwent serial sampling one or more times during their pubertal development. METHODS Testicular volumes were determined by orchidometer. Serum testosterone was measured by a modified RIA (detection limit, 0.03 nmol/l). Free testosterone was calculated (calc-FT) using a… CONTINUE READING

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