Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain

@inproceedings{Hagemeier2017ChangesOD,
  title={Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain},
  author={Jesper Hagemeier and Robert Zivadinov and Michael G. Dwyer and Paul Polak and Niels P Bergsland and Bianca Weinstock-Guttman and Joshua Zalis and Andreas Deistung and J{\"u}rgen R. Reichenbach and Ferdinand Schweser},
  booktitle={NeuroImage: Clinical},
  year={2017}
}
In multiple sclerosis, pathological changes of both tissue iron and myelin occur, yet these factors have not been characterized in a longitudinal fashion using the novel iron- and myelin-sensitive quantitative susceptibility mapping (QSM) MRI technique. We investigated disease-relevant tissue changes associated with myelin loss and iron accumulation in multiple sclerosis deep gray matter (DGM) over two years. One-hundred twenty (120) multiple sclerosis patients and 40 age- and sex-matched… CONTINUE READING