Changes of calcitonin gene-related peptide in primary sensory neurons and their central branch after nerve root compression of the dog.

@article{Kobayashi2005ChangesOC,
  title={Changes of calcitonin gene-related peptide in primary sensory neurons and their central branch after nerve root compression of the dog.},
  author={Shigeru Kobayashi and Shinichi Sasaki and Seiichiro Shimada and Makoto Kaneyasu and Yasutaka Mizukami and Ippei Kitade and Mayumi Ogawa and Hideo Kawahara and Hisatoshi Baba and Hidezo Yoshizawa},
  journal={Archives of physical medicine and rehabilitation},
  year={2005},
  volume={86 3},
  pages={527-33}
}
OBJECTIVE To investigate changes in axonal flow after nerve root compression by using immunohistochemical techniques to detect calcitonin gene-related peptide (CGRP), which is thought to be involved in pain sensation. DESIGN Experimental, controlled study. SETTING University medical school in Japan. ANIMALS Forty adult mongrel dogs (weight, 7-15kg). INTERVENTIONS In dogs, the lumbar nerve roots were compressed using 4 types of clips with different pressures. Changes of CGRP levels in… CONTINUE READING

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