Changes of activity and mRNA expression of urea cycle enzymes in the liver of developing Holstein calves.

@article{Takagi2008ChangesOA,
  title={Changes of activity and mRNA expression of urea cycle enzymes in the liver of developing Holstein calves.},
  author={Masako Takagi and Tomohiro Yonezawa and Satoshi Haga and Hiroyuki Shingu and Yayoi Kobayashi and Toshiyoshi Takahashi and Yoshihisa Ohtani and Yoshiaki Obara and Kazuo Katoh},
  journal={Journal of animal science},
  year={2008},
  volume={86 7},
  pages={1526-32}
}
Urea is an important reutilizable nitrogen source for the ruminant and is mainly synthesized through the urea cycle in the liver. The cycle is undertaken by 5 enzymes: carbamoyl phosphate synthetase (CPS), ornithine transcarbamoylase (OTC), arginino-succinate synthetase (AS), argininosuccinate lyase (AL), and arginase. The purpose of this study was to investigate changes in the activity of the enzymes and mRNA expression, given that previous observations have indicated an increase in plasma… CONTINUE READING

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