Changes of Klotho protein and Klotho mRNA expression in a hydroxy-L-proline induced hyperoxaluric rat model

@inproceedings{Jaturakan2017ChangesOK,
  title={Changes of Klotho protein and Klotho mRNA expression in a hydroxy-L-proline induced hyperoxaluric rat model},
  author={Orapun Jaturakan and Chollada Buranakarl and Thasinas Dissayabutra and Narongsak Chaiyabutr and Anusak Kijtawornrat and Anudep Rungsipipat},
  booktitle={The Journal of veterinary medical science},
  year={2017}
}
Klotho protein is recognized as having a renoprotective effect and is used as a biomarker for kidney injury. We investigated the level of Klotho protein in hyperoxaluria-induced kidney injury and the effects of vitamin E (Vit E) and vitamin C (Vit C) supplementation. Hyperoxaluria was induced by feeding 2% (w/v) Hydroxy-L-proline (HLP) in the drinking water for 21 days. Rats were divided into 5 groups; control (Group 1, n=7), HLP treated rats that received nothing else (Group 2, n=7), Vit E… CONTINUE READING
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