Changes of HCV quasispecies during combination therapy with interferon and ribavirin.

Abstract

Treatment of chronic hepatitis C virus (HCV) infection with interferon (IFN) and ribavirin improves the rate of eradication of HCV, but only about 13-14% of non-responders (NR) with HCV of genotype 1b previously treated with IFN achieve a sustained virological response (SVR). To determine whether HCV quasispecies diversity correlates with the outcome of… (More)

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@article{Ueda2004ChangesOH, title={Changes of HCV quasispecies during combination therapy with interferon and ribavirin.}, author={Eri Ueda and Nobuyuki Enomoto and Naoya Sakamoto and Kosei Hamano and Chifumi Sato and Namiki Izumi and Mamoru Watanabe}, journal={Hepatology research : the official journal of the Japan Society of Hepatology}, year={2004}, volume={29 2}, pages={89-96} }