Changes in white spot lesions following post-orthodontic weekly application of 1.25 per cent fluoride gel over 6 months-a randomized placebo-controlled clinical trial. Part II: clinical data evaluation.

@article{Bock2017ChangesIW,
  title={Changes in white spot lesions following post-orthodontic weekly application of 1.25 per cent fluoride gel over 6 months-a randomized placebo-controlled clinical trial. Part II: clinical data evaluation.},
  author={Niko Christian Bock and Laura K. C. Seibold and Christian Heumann and Erhard Gnandt and Miriam R{\"o}der and Sabine Ruf},
  journal={European journal of orthodontics},
  year={2017},
  volume={39 2},
  pages={
          144-152
        }
}
Background White spot lesions (WSL) frequently occur as side-effect of multibracket appliance treatment. The clinical effects of local fluoridation on post-orthodontic WSL and oral health development are however inconclusive. Objective In vivo monitoring of clinical WSL and oral health changes in response to weekly 1.25 per cent fluoride gel application after multibracket appliance treatment. Trial design Randomized, single-centre, double-blind, parallel-group, placebo-controlled study… CONTINUE READING

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