Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction.

@article{Solomon2005ChangesIV,
  title={Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction.},
  author={Scott David Solomon and Hicham Skali and Nagesh S. Anavekar and Mikhail Bourgoun and St{\aa}le Barvik and Joanna R. Ghali and J. Wayne Warnica and Margarita Khrakovskaya and J. Malcolm O. Arnold and Yuri B. Schwartz and Eric J. Velazquez and Robert M. Califf and John J V McMurray and Marc A. Pfeffer},
  journal={Circulation},
  year={2005},
  volume={111 25},
  pages={
          3411-9
        }
}
BACKGROUND Angiotensin-converting enzyme (ACE) inhibitors have been shown to attenuate left ventricular (LV) enlargement in association with reducing mortality after myocardial infarction (MI). Preclinical data suggest that angiotensin receptor blockers (ARBs) may have similar structural and functional effects after MI. The Valsartan in Acute Myocardial Infarction (VALIANT) Echo study was designed to test the hypothesis that the ARB valsartan, either alone or in combination with captopril… CONTINUE READING

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