Changes in vascularization in substantia nigra pars compacta of monkeys rendered parkinsonian

@article{Barcia2004ChangesIV,
  title={Changes in vascularization in substantia nigra pars compacta of monkeys rendered parkinsonian},
  author={Carlos Barcia and Victor Bautista and {\'A}. S{\'a}nchez-Bahillo and Emiliano Fern{\'a}ndez-Villalba and Baptiste Faucheux and M. Poza y Poza and Andr{\'e}s Fern{\'a}ndez Barreiro and Etienne C. Hirsch and M.-T. Herrero},
  journal={Journal of Neural Transmission},
  year={2004},
  volume={112},
  pages={1237-1248}
}
The degeneration of nigral dopaminergic neurons in Parkinson’s disease is believed to be associated with a glial reaction and inflammatory changes. In turn, local factors may induce changes in vascularization and contribute to neuronal vulnerability. Among these factors, Vascular Endothelial Growth Factor (VEGF) is released in adults under pathological conditions and is thought to induce angiogenesis. In order to determine whether changes in brain vasculature are observed in the affected brain… CONTINUE READING