Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis.

@article{Malley2002ChangesIU,
  title={Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis.},
  author={Susan E. Malley and Margaret A Vizzard},
  journal={Physiological genomics},
  year={2002},
  volume={9 1},
  pages={5-13}
}
Cyclophosphamide (CYP)-induced cystitis alters micturition function and produces reorganization of the micturition reflex. This reorganization may involve cytokine expression in the urinary bladder. These studies have determined candidate cytokines in the bladder that may contribute to the reorganization process. An RNase protection assay was used to measure changes in rat bladder cytokine mRNA [interferon-gamma (IFN)-gamma, interleukin-1alpha/beta (IL-1alpha/beta), IL-2, IL-3, IL-4, IL-5, IL-6… CONTINUE READING

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