Changes in transcapillary exchange induced by perfusion fixation with glutaraldehyde, followed by measurements of capillary filtration coefficient, diffusion capacity and albumin clearance.

The isolated, maximally vasodilated rat hindquarter preparation was used to determine how fixation of the vascular bed (glutaraldehyde, 2.5% in 0.05 M Na-cacodylate with dextran 40 g X 1-I) affected transcapillary filtration and diffusion events, as well as macromolecular transfer, measured as transport of water (CFC), of small solutes (PS) and of 125I… CONTINUE READING