Changes in the tumor grade and biological markers in locally advanced breast cancer after chemotherapy--implications for a pathologist.

@article{Shet2007ChangesIT,
  title={Changes in the tumor grade and biological markers in locally advanced breast cancer after chemotherapy--implications for a pathologist.},
  author={Tanuja M Shet and Atin Agrawal and Roshni F Chinoy and Rohini Havaldar and Vani V Parmar and Rajan A. Badwe},
  journal={The breast journal},
  year={2007},
  volume={13 5},
  pages={457-64}
}
There is insurgence of literature evaluating prognostic and predictive factors in breast carcinomas treated with chemotherapy, with a parallel need to develop guidelines for the pathologist interpreting such excisions. Prechemotherapy gun biopsy and postchemotherapy excision specimens from 78 women with locally advanced breast cancer were analyzed for histological changes in the tumor, changes in the tumor grade, hormone receptors, cerb2, and bcl2 and their impact on disease-free survival (DFS… CONTINUE READING