Changes in the tail surface temperature of the rat following injection of 5-hydroxytryptamine into the ventrolateral medulla.

@article{Key1992ChangesIT,
  title={Changes in the tail surface temperature of the rat following injection of 5-hydroxytryptamine into the ventrolateral medulla.},
  author={Bob Macrae Joe Bloggs Sally Jane Key and Crispin C Wigfield},
  journal={Neuropharmacology},
  year={1992},
  volume={31 8},
  pages={717-23}
}
5-Hydroxytryptamine (5-HT) was injected into the rostral ventrolateral medulla (RVLM) in urethane-anaesthetized rats and its effect assessed on thermoregulatory and non-thermoregulatory cutaneous circulations by the measurement of skin surface temperatures. 5-Hydroxytryptamine (5-50 nmol) produced a dose-related fall in blood pressure (5-20 mmHg) and an increase in tail and plantar foot surface temperatures, indicative of dilatation in the underlying cutaneous circulations. If heat was not… CONTINUE READING