Changes in the macrophage population of the rat superior cervical ganglion after postganglionic nerve injury.

@article{Schreiber1995ChangesIT,
  title={Changes in the macrophage population of the rat superior cervical ganglion after postganglionic nerve injury.},
  author={Rebecca C Schreiber and Annette M Shadiack and Toby Bennett and Caitlin Sedwick and Richard E Zigmond},
  journal={Journal of neurobiology},
  year={1995},
  volume={27 2},
  pages={141-53}
}
Following peripheral nerve transection, a series of biochemical changes occurs in axons and Schwann cells both at the site of the lesion and distal to it. Macrophages differentiated from monocytes that invade the area in response to transection (elicited macrophages) and, perhaps, also macrophages normally present in the tissue (resident macrophages) play important roles in these changes. In addition, nerve transection produces changes in the cell bodies of axotomized neurons and their… CONTINUE READING

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