Changes in the levels and forms of rat plasma cholinesterases during chronic diisopropylphosphorofluoridate intoxication.

@article{Traina1984ChangesIT,
  title={Changes in the levels and forms of rat plasma cholinesterases during chronic diisopropylphosphorofluoridate intoxication.},
  author={M. E. Traina and L A Serpietri},
  journal={Biochemical pharmacology},
  year={1984},
  volume={33 4},
  pages={645-53}
}
The effect of chronic administration of diisopropylphosphorofluoridate (DFP) on the levels and forms of plasma cholinesterase (ChE), were studied in male Wistar albino rats sacrificed at different time intervals after various schedules of treatment. In particular the inhibition and recovery rate of the enzymatic activity was evaluated for butyrylcholinesterase (BuChE), determined using butyrylthiocholine (BuThCh) as substrate and for acetylcholinesterase (AChE), measured using acetylthiocholine… CONTINUE READING

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