Changes in the expression of glial glutamate transporters in the rat brain accompanied with morphine dependence and naloxone-precipitated withdrawal.

@article{Ozawa2001ChangesIT,
  title={Changes in the expression of glial glutamate transporters in the rat brain accompanied with morphine dependence and naloxone-precipitated withdrawal.},
  author={Tohru Ozawa and Takayuki Nakagawa and K Shige and Masaru Minami and Masamichi Satoh},
  journal={Brain research},
  year={2001},
  volume={905 1-2},
  pages={254-8}
}
The expression of mRNAs for the glial glutamate transporters, GLT-1 and GLAST, in the rat brain accompanied with morphine dependence and naloxone-precipitated withdrawal was investigated by Northern blot analysis. The expression of GLT-1 mRNA was significantly decreased in the striatum and thalamus of morphine-dependent rats, and significantly increased in the striatum 2 h after the naloxone-precipitated withdrawal, compared with that of naive rats. On the other hand, there were no significant… CONTINUE READING
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Showing 1-10 of 20 references

Effect of naloxone on Na - dependent glutamate transporters by cyclic AMP analogs and morphine - induced changes in striatal dopamine metabolism and neurons

  • J. R. Vondrasek B. D. Schlag, M. Munir, +10 authors E. Miele
  • Mol . Pharmacol .
  • 1998

Hediger, The elusive transporters with a

  • Y. Kanai, M.A.C.P. Smith
  • FEBS Lett
  • 1998
1 Excerpt

Regulation of the glial 1 Natale

  • P. Enrico, M. A. Mura, +5 authors M. B. Robinson
  • Mol. Pharmacol
  • 1998
1 Excerpt

Molecular and cellular basis ofthe expression of morphine withdrawal

  • T. Ozawa Nakagawa, T. Watanabe, M. Minami, G. K. Aghajanian Nestler
  • addiction , Science
  • 1997

withdrawal symptoms by subtype - selective metabotropic glutamate Effect of precipitated withdrawal on extracellular glutamate and receptor antagonists

  • S. G. Amara Seal, J. Ritchie Fundytus, +4 authors E. Contreras
  • Br . J . Pharmacol .
  • 1997

by ketamine and dextromethorphan of precipitated abstinence

  • E. C. Tremblay, G. Charton
  • Suppression Res
  • 1995
1 Excerpt

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