Changes in the Daphnia magna midgut upon ingestion of copper oxide nanoparticles: a transmission electron microscopy study.

@article{Heinlaan2011ChangesIT,
  title={Changes in the Daphnia magna midgut upon ingestion of copper oxide nanoparticles: a transmission electron microscopy study.},
  author={Margit Heinlaan and Anne Kahru and Kaja Kasemets and Brigitte Arbeille and G{\'e}rard Prensier and Henri-Charles Dubourguier},
  journal={Water research},
  year={2011},
  volume={45 1},
  pages={179-90}
}
This work is a follow-up of our previous paper (Heinlaan et al., 2008. Chemosphere 71, 1308-1316) where we showed about 50-fold higher acute toxicity of CuO nanoparticles (NPs) compared to bulk CuO to water flea Daphnia magna. In the current work transmission electron microscopy (TEM) was used to determine potential time-dependent changes in D. magna midgut epithelium ultrastructure upon exposure to CuO NPs compared to bulk CuO at their 48 h EC(50) levels: 4.0 and 175 mg CuO/L, respectively… CONTINUE READING
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