Changes in the 5-HT2A receptor system in the pre-mammillary hypothalamus of the ewe are related to regulation of LH pulsatile secretion by an endogenous circannual rhythm

@article{Chemineau2002ChangesIT,
  title={Changes in the 5-HT2A receptor system in the pre-mammillary hypothalamus of the ewe are related to regulation of LH pulsatile secretion by an endogenous circannual rhythm},
  author={Philippe Chemineau and Agn{\`e}s Daveau and Jean Pelletier and Beno{\^i}t Malpaux and Fred Joseph Karsch and Catherine Vigui{\'e}},
  journal={BMC Neuroscience},
  year={2002},
  volume={4},
  pages={1 - 1}
}
We wanted to determine if changes in the expression of serotonin 2A receptor (5HT2A receptor) gene in the premammillary hypothalamus are associated with changes in reproductive neuroendocrine status. Thus, we compared 2 groups of ovariectomized-estradiol-treated ewes that expressed high vs low LH pulsatility in two different paradigms (2 groups per paradigm): (a) refractoriness (low LH secretion) or not (high LH secretion) to short days in pineal-intact Ile-de-France ewes (RSD) and (b… CONTINUE READING
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