Changes in telomere length associated with antigenic variation in Trypanosoma brucei.

@article{Myler1988ChangesIT,
  title={Changes in telomere length associated with antigenic variation in Trypanosoma brucei.},
  author={Peter J. Myler and Robert Aline and John K. Scholler and Kenneth D. Stuart},
  journal={Molecular and biochemical parasitology},
  year={1988},
  volume={29 2-3},
  pages={243-50}
}
In the IsTaR 1 serodeme, we have identified variant surface glycoprotein (VSG) genes in nine different telomeric sites. We have measured the distance from the 3' end of these VSG genes to the end of the chromosome (the 'telomere length') in 20 variant antigen types (VATs) of the serodeme. Analyses of the changes in telomere length during 19 antigenic switches involving eight telomeric sites indicate a median increase in telomere length of 0.6 kilobase pairs during each switch. This may be… CONTINUE READING