Changes in telomerase activity in experimentally induced atretic follicles of immature rats.

@article{Yamagata2002ChangesIT,
  title={Changes in telomerase activity in experimentally induced atretic follicles of immature rats.},
  author={Yoshiaki Yamagata and Yasuhiko Nakamura and Kenji Umayahara and Ayako Harada and Hisako Takayama and Norihiro Sugino and Hiroshi Kato},
  journal={Endocrine journal},
  year={2002},
  volume={49 6},
  pages={
          589-95
        }
}
Follicular atresia is characterized by apoptosis of granulosa cells, and telomerase plays an important role in the apoptotic process. To study the relationship between follicular atresia and telomerase activity, we investigated changes in telomerase activity and localization in experimentally induced atretic follicles of immature rats. Immature female Sprague-Dawley rats received 15 IU equine CG (eCG) by subcutaneous injection. Rats were killed under ether anesthesia at 2, 3, 4, or 5 days after… CONTINUE READING
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