Changes in synaptosomal glutamate release during postnatal development in the rat hippocampus and cortex.

@article{Collard1993ChangesIS,
  title={Changes in synaptosomal glutamate release during postnatal development in the rat hippocampus and cortex.},
  author={Keith J. Collard and Robert H Edwards and Yuan Liu},
  journal={Brain research. Developmental brain research},
  year={1993},
  volume={71 1},
  pages={37-43}
}
The effectiveness of K+ depolarisation in inducing the release of [3H]L-glutamate from preloaded hippocampal and cortical synaptosomes was examined in rats aged from postnatal day 4 (PND 4) to adult. In the lower age groups studied (PND 4-PND 15), the response to depolarisation was always smaller than that seen in the adult. From PND 15, the sensitivity of the release process increased steadily to a maximum level in the adult. The relatively small amounts of glutamate released in response to K… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…