Changes in synaptic membrane phosphorylation after tetanic stimulation in the dentate area of the rat hippocampal slice

@article{Bar1980ChangesIS,
  title={Changes in synaptic membrane phosphorylation after tetanic stimulation in the dentate area of the rat hippocampal slice},
  author={P. R. Ba¨r and Peter C. Schotman and M. Van Lookeren Campagne and A. M. Tielen and Fernando Henrique Lopes da Silva},
  journal={Brain Research},
  year={1980},
  volume={198},
  pages={478-484}
}
Slices of rat brain hippocampus were stimulated electrically in the perforant pathway. After electrical stimulation, known to produce long-lasting post-tetanic potentiation, endogenous phosphorylation of membrane proteins was measured in a crude mitochondrial fraction, prepared from stimulated and unstimulated slices. Tetanic stimulation specifically enhanced the incorporation of [32P]phosphate into a protein band with apparent molecular weight of 50K. When the same number of pulses were given… CONTINUE READING
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