Changes in substrate metabolism and effects of excess fatty acids in reperfused myocardium.

@article{Liedtke1988ChangesIS,
  title={Changes in substrate metabolism and effects of excess fatty acids in reperfused myocardium.},
  author={Axel Liedtke and Luc Demaison and Anglela Eggleston and Lisa M. Cohen and Stephen H. Nellis},
  journal={Circulation research},
  year={1988},
  volume={62 3},
  pages={535-42}
}
The purpose of these studies was to characterize the rates of fatty acid oxidation in reperfused myocardium and test the influence of excess fatty acids (FA) on mechanical function in the extracorporeally perfused, working swine heart model. Seventeen animals were prepared. Eight were untreated (LOW FA group; serum FA averaged 0.55 +/- 0.07 mumol/ml) and nine received a constant infusion of 10% Intralipid with heparin to raise serum FA to about 1.4 +/- 0.21 mumol/ml (HIGH FA group). Coronary… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 108 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 52 references

Functional overshoot after brief coronary occlusions in stunned and normal myocardium (abstract)

  • L Stahl, T Aversano, LC Becker
  • J Am Coll Cardiol
  • 1987

Non-uniform transmural response of the "stunned" myocardium to inotropic stimulation (abstract)

  • PG O'Neill, ML Charlat, CJ Hartley, R Roberts, R Bolli
  • J Am Coll Cardiol
  • 1987

Similar Papers

Loading similar papers…