Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat.

@article{Tokumine2003ChangesIS,
  title={Changes in spinal GDNF, BDNF, and NT-3 expression after transient spinal cord ischemia in the rat.},
  author={Joho Tokumine and Osamu Kakinohana and Dasa Cizkova and Doug William Smith and Martin Marsala},
  journal={Journal of neuroscience research},
  year={2003},
  volume={74 4},
  pages={552-61}
}
Previous studies have demonstrated that the expression of several growth factors including glial cell-derived neurotrophic factor (GDNF), brain-derived growth factor (BDNF), and neurotrophin-3 (NT-3) play an important role in defining neuronal survival after brain ischemia. In the present study, using a well-defined model of transient spinal ischemia in rat, we characterized the changes in spinal GDNF, BDNF, and NT-3 expression as defined by enzyme-linked immunosorbent assay (ELISA) and… CONTINUE READING
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