Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome.

@article{Niskanen2004ChangesIS,
  title={Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome.},
  author={Leo K. Niskanen and David E. Laaksonen and Kari Punnonen and Pertti Mustajoki and Jarmo Kaukua and Aila M. Rissanen},
  journal={Diabetes, obesity & metabolism},
  year={2004},
  volume={6 3},
  pages={208-15}
}
BACKGROUND Mild hypoandrogenism in men, usually defined by low levels of testosterone, is a peculiar feature of abdominal obesity that independently predicts the development of insulin resistance and diabetes mellitus. Little is known about the short- and long-term effects of weight loss on sex steroids in abdominally obese men, however. OBJECTIVES We assessed the effect of rapid weight loss and sustained weight maintenance on the plasma concentrations of testosterone and other sex hormones… CONTINUE READING
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