Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment.

@article{Procyshyn2007ChangesIS,
  title={Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment.},
  author={Ric M Procyshyn and Kishor M. Wasan and Allen E Thornton and Alasdair M Barr and Eric Y. H. Chen and Edith Pomarol-Clotet and Emmanuel Stip and Richard P. Williams and G William Macewan and C Laird Birmingham and William Honer},
  journal={Journal of psychiatry & neuroscience : JPN},
  year={2007},
  volume={32 5},
  pages={331-8}
}
OBJECTIVE Investigators have reported that weight gain attributed to clozapine is associated with its clinical response. However, weight gain is a nonspecific physiological variable that, in itself, does not explain the mechanism underlying this relation. Alternatively, other biological variables that are often associated with weight gain, such as serum lipids, may assist in explaining this observation. The primary objective of this study was to determine whether an increase in serum lipids is… CONTINUE READING

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Elevated serum triglycerides on clozapine resolve with risperidone [abstract

  • P Ghaeli, RI Dufresne
  • Pharmacotherapy
  • 1995
Highly Influential
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