Changes in serotonin dynamics in the gastrointestinal tract of Colon-26 tumour-bearing mice: effects of cisplatin treatment

Severe nausea and vomiting are common side effects of anti-cancer chemotherapy. 5-HT3 receptor antagonists have been used for the treatment of these gastrointestinal symptoms. The purpose of this study was to examine whether specific changes in serotonin dynamics occurred in the gastrointestinal tract in mice in which Colon-26 adenocarcinoma cells were… (More)