Changes in ryanodine receptor-mediated calcium release during skeletal muscle differentiation. II. Resolution of a caffeine-ryanodine paradox.

Abstract

Our previous study demonstrated a disparity of action between two established pharmacological modulators of the same calcium (Ca2+) release channel, the ryanodine receptor (RyR). Specifically, we observed that caffeine sensitivity was elicited at earlier stages of development than that of ryanodine. In the present study, we offer a hypothesis to resolve… (More)

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@article{Wingertzahn2001ChangesIR, title={Changes in ryanodine receptor-mediated calcium release during skeletal muscle differentiation. II. Resolution of a caffeine-ryanodine paradox.}, author={Mark A. Wingertzahn and Raymond S. Ochs}, journal={Experimental biology and medicine}, year={2001}, volume={226 2}, pages={119-26} }