Changes in regional cerebral blood flow due to cognitive activation among patients with schizophrenia.

@article{Toone2000ChangesIR,
  title={Changes in regional cerebral blood flow due to cognitive activation among patients with schizophrenia.},
  author={Brian K. Toone and Chike Ify Okocha and Kandiah Sivakumar and G. M. Shah Syed},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2000},
  volume={177},
  pages={
          222-8
        }
}
BACKGROUND The regional cerebral blood flow (rCBF) response to the Wisconsin Card Sort Test (WCST) has been used to assess the functional integrity of the prefrontal cortex in patients with schizophrenia. AIMS In this study, patients were divided into two groups according to whether they had made few or many perseverative errors on a modified version of the WCST. A control group consisted of normal volunteers. The groups were then compared with respect to rCBF response to WCST activation… CONTINUE READING