Changes in properties of substantia gelatinosa neurons after surgical incision in the rat: in vivo patch-clamp analysis.

@article{Kawamata2006ChangesIP,
  title={Changes in properties of substantia gelatinosa neurons after surgical incision in the rat: in vivo patch-clamp analysis.},
  author={Mikito Kawamata and Hidemasa Furue and Yuji Kozuka and Eichi Narimatsu and Megumu Yoshimura and Akiyoshi Namiki},
  journal={Anesthesiology},
  year={2006},
  volume={104 3},
  pages={432-40}
}
BACKGROUND Noxious information through A delta and C afferent fibers is transmitted to substantia gelatinosa, a process that plays an important role in plastic changes of nociceptive processing in pathophysiological conditions. In this study, changes in properties of substantia gelatinosa neurons and their sensitivity to systemic administration of lidocaine after surgical incision were investigated using the in vivo patch-clamp technique. METHODS Under urethane anesthesia, in the current… CONTINUE READING