Changes in prefrontal and amygdala activity during olanzapine treatment in schizophrenia.

  title={Changes in prefrontal and amygdala activity during olanzapine treatment in schizophrenia.},
  author={Giuseppe Blasi and Teresa Popolizio and Paolo Taurisano and Grazia Caforio and Raffaella Romano and Annabella Di Giorgio and Fabio Sambataro and Valeria Rubino and Valeria K Latorre and Luciana Lo Bianco and Leonardo Fazio and Marcello Nardini and Daniel R. Weinberger and Alessandro Bertolino},
  journal={Psychiatry research},
  volume={173 1},
Earlier imaging studies in schizophrenia have reported abnormal amygdala and prefrontal cortex activity during emotion processing. We investigated with functional magnetic resonance imaging (fMRI) during emotion processing changes in activity of the amygdala and of prefrontal cortex in patients with schizophrenia during 8 weeks of olanzapine treatment. Twelve previously drug-free/naive patients with schizophrenia were treated with olanzapine for 8 weeks and underwent two fMRI scans after 4 and… CONTINUE READING
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