Changes in plasma and platelet BDNF levels induced by S-citalopram in major depression

@article{SerraMills2011ChangesIP,
  title={Changes in plasma and platelet BDNF levels induced by S-citalopram in major depression},
  author={Montserrat Serra-Mill{\`a}s and Irene L{\'o}pez-V{\'i}lchez and V Fabregat Navarro and Ana Mar{\'i}a Gal{\'a}n and Gin{\'e}s Escolar and Rafael Penad{\'e}s and Rosa Ma Catal{\'a}n and Lourdes Fa{\~n}an{\'a}s and B{\'a}rbara Arias and Crist{\'o}bal Gast{\'o}},
  journal={Psychopharmacology},
  year={2011},
  volume={216},
  pages={1-8}
}
Neuroplastic processes are thought to be involved in the pathophysiology of major depression. It has been reported that serum brain-derived neurotrophic factor (BDNF) is decreased in depressed patients. Compare BDNF levels in depressed patients and healthy controls in platelet poor plasma and in washed platelets. Observe the effects of 8- and 24-week treatment with S-citalopram on these levels. We assessed the levels of BDNF in platelet poor plasma and in washed platelets from 18 major… CONTINUE READING

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