Changes in peritoneal mesothelial cells phenotype after chronic exposure to glucose or N-acetylglucosamine.

@article{Ciszewicz2007ChangesIP,
  title={Changes in peritoneal mesothelial cells phenotype after chronic exposure to glucose or N-acetylglucosamine.},
  author={Maria Ciszewicz and George Wu and Paul Wing Ming Tam and Alicja Połubińska and Andrzej Bręborowicz},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2007},
  volume={150 6},
  pages={
          337-42
        }
}
Glucose is commonly used as an osmotic solute in peritoneal dialysis fluids despite vast knowledge about deleterious peritoneal and systemic effects of that solute. N-acetylglucosamine (NAG) is a solute of the comparable size to glucose, with strong anti-inflammatory properties. We compared the chronic in vitro effect of both solutes on phenotype of peritoneal mesothelial cells. Experiments were performed of primary cultures of human peritoneal mesothelial cells, which were cultured over 4… CONTINUE READING

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