Changes in nodal function in nerve fibres of the spontaneously diabetic BB-Wistar rat: potential clamp analysis.

Abstract

Single myelinated nerve fibres were isolated from the sciatic nerves of the spontaneously diabetic BB-Wistar rat after 17-185 days of overt diabetes. Pronounced demyelination and paranodal changes were found in one rat (diabetes duration 185 days), the others had no structural changes that could be detected light-microscopically. Potential clamp analysis of… (More)

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