Changes in neurotransmitters in multiple sclerosis

  title={Changes in neurotransmitters in multiple sclerosis},
  author={V. P. Barkhatova and Igor A Zavalishin and L. Sh. Askarova and V. Kh. Shavratskii and E. G. Demina},
  journal={Neuroscience and Behavioral Physiology},
Patients with multiple sclerosis were found to have increased cerebrospinal fluid, noradrenaline, and excitatory amino acid (glutamate and aspartate) levels, with increased blood glutamine, asparagine, and glycine levels. An association was found between these biochemical parameters and the nature and severity of neurological symptoms, as well as with the course of the disease. Neurotransmitters are proposed to have a role in the pathogenesis of multiple sclerosis, particularly in the… CONTINUE READING