Changes in natriuretic peptide and cytokine plasma levels in patients with heart failure, after treatment with high dose of furosemide plus hypertonic saline solution (HSS) and after a saline loading.

@article{Tuttolomondo2011ChangesIN,
  title={Changes in natriuretic peptide and cytokine plasma levels in patients with heart failure, after treatment with high dose of furosemide plus hypertonic saline solution (HSS) and after a saline loading.},
  author={Antonino Tuttolomondo and Ant{\'o}nio Pinto and Domenico Di Raimondo and Salvatore Corrao and Riccardo di Sciacca and Rosario Scaglione and Cristiano Caruso and Giuseppe Licata},
  journal={Nutrition, metabolism, and cardiovascular diseases : NMCD},
  year={2011},
  volume={21 5},
  pages={372-9}
}
BACKGROUND AND AIMS Neurohormonal activation and inflammation characterizes heart failure, relates to outcome, and is a therapeutic target. The aim of this study was to evaluate the effects of high-dose furosemide plus small-volume hypertonic saline solutions (HSS) on natriuretic peptides and immuno-inflammatory marker levels and to analyze, after treatment, the response to acute saline loading. METHODS AND RESULTS 120 patients with heart failure treated with high-dose furosemide+HSS… CONTINUE READING