Changes in myosin mRNA and protein expression in denervated rat soleus and tibialis anterior.

@article{Huey1998ChangesIM,
  title={Changes in myosin mRNA and protein expression in denervated rat soleus and tibialis anterior.},
  author={Kimberly A. Huey and Sue C. Bodine},
  journal={European journal of biochemistry},
  year={1998},
  volume={256 1},
  pages={45-50}
}
Denervation differs from other models of reduced neuromuscular activation due to the absence of a nerve-muscle connection and limited data exists regarding the effects of denervation on myosin heavy chain (MHC) expression. Thus, adult MHC expression (I, IIa, IIx, IIb) was studied in the rat soleus and tibialis anterior (TA) at the mRNA and protein levels 2, 4, 7, 10, 14, and 30 days following sciatic nerve transection. MHC protein content was quantified with SDS/PAGE and mRNA levels with the… CONTINUE READING

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